Research Interests
Research projects typically involve:
- Poorly water-soluble and BCS class 2 drug delivery using nanotechnology
- Biopharmaceuticals, peptides, and large molecules drug delivery using nanotechnology
- Physicochemical characterization of formulations
- In vitro cellular testing of drugs and formulations (safety, activity, and proof of concept)
With potential collaborations on in vivo conceptualization and synthesis of ligands for drug targeting.
Current Research Opportunities
- Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery
- Development of antioxidants-based nanoparticles for topical application
- Development of next-generation nanoparticles loaded hydrogels containing multiple active agents for improved treatment of bacterial infections
- Development of anti-inflammatory-based nanoparticles for topical treatment of psoriasis
Public outreach & key achievements
Indocyanine green J-aggregate (IJA) theranostics: Challenges and opportunities
Alotaibi, H., Hatahet, T. & Al-Jamal, W. T.
International Journal of Pharmaceutics 661, (2024) 9 p., .
Liposomes, lipid nanocapsules and smartCrystals®: a comparative study for an effective quercetin delivery to the skin
Hatahet T., Morel Mr., Hommoss A., Devoisselle JM., Müller R. H., Bégu S.
International Journal of Pharmaceutics 542 (2018) 176–185
Molybdenum cluster loaded PLGA nanoparticles: An innovative theranostic approach for the treatment of ovarian cancer
Brandhonneur N., Hatahet T., Amela-Cortes Mr., Molard Y., Cordier S., Dollo G.
European Journal of Pharmaceutics and Biopharmaceutics 125 (2018) 95–105
Quercetin topical application: from conventional dosage forms toward nanodosage Forms
Hatahet T., Morel Mr., Hommoss A. Devoisselle, J.M., Müller, R.H., Bégu S.
European Journal of Pharmaceutics and Biopharmaceutics 108 (2016) 41-53,
Dermal quercetin smartCrystals®: formulation development, antioxidant activity and cellular safety.
Hatahet, T., Morel, M., Hommoss, A., Dorandeu, C., Müller, R. H., Bégu, S.
European Journal of Pharmaceutics and Biopharmaceutics 102 (2016) 51-63
Research students
| PhD Title | Development of nano photothermal therapy for skin cancer |
| Name | Siyang Wu |
| Country | PR China |
| PhD Title | Engineering Biodegradable Photothermal Nanoparticles for Cancer Therapy |
| Name | Hamoud Alotaibi |
| Country | PR China |
| PhD Title | Molecularly Imprinted Nanoparticles for Cancer Immunotherapy |
| Name | Minao Zhang |
| Country | PR China |
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